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  8. SKF 86002 dihydrochloride, Tocris Bioscience™

SKF 86002 dihydrochloride, Tocris Bioscience™

Catalog Number 200810
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Quantity:
10 mg
50 mg
This item is not returnable. View return policy
116339-68-5
C16H14Cl2FN3S
370.267
GQQCNUNCYVXBTF-UHFFFAOYSA-N
skf 86002 dihydrochloride, 6-4-fluorophenyl-2,3-dihydro-5-4-pyridinyl imidazo 2,1-b thiazole dihydrochloride, 6-4-fluorophenyl-5-pyridin-4-yl-2,3-dihydroimidazo 2,1-b thiazole dihydrochloride
10339107
6-(4-fluorophenyl)-5-pyridin-4-yl-2,3-dihydroimidazo[2,1-b][1,3]thiazole;dihydrochloride
C1CSC2=NC(=C(N21)C3=CC=NC=C3)C4=CC=C(C=C4)F.Cl.Cl
This item is not returnable. View return policy
116339-68-5
C16H14Cl2FN3S
370.267
GQQCNUNCYVXBTF-UHFFFAOYSA-N
skf 86002 dihydrochloride, 6-4-fluorophenyl-2,3-dihydro-5-4-pyridinyl imidazo 2,1-b thiazole dihydrochloride, 6-4-fluorophenyl-5-pyridin-4-yl-2,3-dihydroimidazo 2,1-b thiazole dihydrochloride
10339107
6-(4-fluorophenyl)-5-pyridin-4-yl-2,3-dihydroimidazo[2,1-b][1,3]thiazole;dihydrochloride
C1CSC2=NC(=C(N21)C3=CC=NC=C3)C4=CC=C(C=C4)F.Cl.Cl

Description

p38 MAPK inhibitor; anti-inflammatory agent

Inhibitor of p38 MAP kinase (IC50 = 0.1 - 1 μM). Potently inhibits LPS-induced IL-1 and TNF-α production in human monocytes (IC50 = 1 μM). Also inhibits 5-lipoxygenase- and cyclooxygenase-mediated arachidonic acid metabolism in RBL-1 cells (IC50 values are 10 and 100 μM respectively). Anti-inflammatory following oral administration in vivo.
Quantity 10 mg
Formula Weight 370.27
Percent Purity >98%
Chemical Name or Material SKF 86002 dihydrochloride

Safety and Handling

Recommended Storage Desiccate at +4°C
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