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  8. SKPin C1, Tocris Bioscience™

SKPin C1, Tocris Bioscience™

Catalog Number 481710
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Quantity:
10 mg
50 mg
This item is not returnable. View return policy
432001-69-9
C18H13BrN2O4S2
465.336
IYCJJVVXEHZJHE-CHHVJCJISA-N
skp2 inhibitor c1, skpin c1, 2-4-bromo-2-z-4-oxo-3-pyridin-3-ylmethyl-2-sulfanylidene-1,3-thiazolidin-5-ylidene methyl phenoxy acetic acid, skp2 inhibitor c1 skpin c1, 4-bromo-2-z-4-oxo-3-pyridin-3-ylmethyl-2-thioxo-1,3-thiazolidin-5-ylidene methyl phenoxy acetic acid, 2-4-bromo-2-4-oxo-3-3-pyridinylmethyl-2-thioxo-5-thiazolidinylidene methyl phenoxy acetic acid
5733396
2-[4-bromo-2-[(Z)-[4-oxo-3-(pyridin-3-ylmethyl)-2-sulfanylidene-1,3-thiazolidin-5-ylidene]methyl]phenoxy]acetic acid
C1=CC(=CN=C1)CN2C(=O)C(=CC3=C(C=CC(=C3)Br)OCC(=O)O)SC2=S
This item is not returnable. View return policy
432001-69-9
C18H13BrN2O4S2
465.336
IYCJJVVXEHZJHE-CHHVJCJISA-N
skp2 inhibitor c1, skpin c1, 2-4-bromo-2-z-4-oxo-3-pyridin-3-ylmethyl-2-sulfanylidene-1,3-thiazolidin-5-ylidene methyl phenoxy acetic acid, skp2 inhibitor c1 skpin c1, 4-bromo-2-z-4-oxo-3-pyridin-3-ylmethyl-2-thioxo-1,3-thiazolidin-5-ylidene methyl phenoxy acetic acid, 2-4-bromo-2-4-oxo-3-3-pyridinylmethyl-2-thioxo-5-thiazolidinylidene methyl phenoxy acetic acid
5733396
2-[4-bromo-2-[(Z)-[4-oxo-3-(pyridin-3-ylmethyl)-2-sulfanylidene-1,3-thiazolidin-5-ylidene]methyl]phenoxy]acetic acid
C1=CC(=CN=C1)CN2C(=O)C(=CC3=C(C=CC(=C3)Br)OCC(=O)O)SC2=S

Description

Inhibits Skp2-mediated p27 degradation; induces cell cycle arrest

Inhibitor of Skp2-mediated p27 degradation. Induces p27 accumulation in metastatic melanoma cell lines. Promotes G1/S cell cycle arrest in T47D cells and LNCaP cells; induces G2/M cell cycle arrest in MCF-7 cells.
Quantity 10 mg
Formula Weight 465.34
Percent Purity >98%
Chemical Name or Material SKPin C1

Safety and Handling

Recommended Storage Store at +4°C
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