Invitrogen™ SLC10A2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5100125

Catalog No. PIPA5100125

Description

Antibody detects endogenous levels of total ASBT.

This gene encodes a sodium/bile acid cotransporter. This transporter is the primary mechanism for uptake of intestinal bile acids by apical cells in the distal ileum. Bile acids are the catabolic product of cholesterol metabolism, so this protein is also critical for cholesterol homeostasis. Mutations in this gene cause primary bile acid malabsorption (PBAM); mutations in this gene may also be associated with other diseases of the liver and intestines, such as familial hypertriglyceridemia (FHTG).

Specifications

• Antigen: SLC10A2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Slc10a2
• Gene Alias: Apical sodium-dependent bile acid transporter; ASBT; IBAT; ileal apical sodium-dependent bile acid transporter; ileal Na(+)/bile acid cotransporter; ileal sodium/bile acid cotransporter; Ileal sodium-dependent bile acid transporter; ISBAT; ISBT; Na(+)-dependent ileal bile acid transporter; NTCP2; PBAM; Slc10a2; Sodium/taurocholate cotransporting polypeptide, ileal; sodium/taurocholate-cotransporting polypeptide, ileal; solute carrier family 10 (sodium/bile acid cotransporter family), member 2; solute carrier family 10 (sodium/bile acid cotransporter), member 2; solute carrier family 10 member 2; solute carrier family 10, member 2
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 20494, 6555
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: P70172, Q12908
• Gene Symbols: Slc10a2
• Immunogen: A synthesized peptide derived from human SLC10A2(Accession Q12908), corresponding to amino acid residues P332-K348.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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