Invitrogen™ SLC29A3 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA538039

Catalog No. PIPA538039

Description

A recommended positive control is mouse bladder tissue lysate. At least two isoforms of SLC29A3 are known to exist; this antibody will detect both isoforms. SLC29A3 antibody is not expected to cross-react with other SLC29 proteins.

SLC29A3 is a member of the equilibrative nucleoside transporter family which plays a key role in nucleoside and nucleobase uptake for salvage pathways of nucleotide synthesis. SLC29A3 is a transmembrane glycoprotein that localizes to the lysosomal membrane and is a broad selectivity, low affinity nucleoside transporter. Mutations in the SLC29A3 gene have been associated with H syndrome, which is characterized by cutaneous hyperpigmentation and hypertrichosis, hepatosplenomegaly, heart anomalies, and hypogonadism. A related disorder, PHID (pigmented hypertrichosis with insulin-dependent diabetes mellitus), has also been associated with mutations at this locus.

Specifications

• Antigen: SLC29A3
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: SLC29A3
• Gene Alias: 4933435C21Rik; AW987637; Ent3; Equilibrative nucleoside transporter 3; HCLAP; hENT3; HJCD; mENT3; PHID; Slc29a3; solute carrier family 29 (equilibrative nucleoside transporter), member 3; solute carrier family 29 (nucleoside transporters), member 3; solute carrier family 29 member 3; UNQ717/PRO1380
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 353307, 55315, 71279
• Content And Storage: Maintain refrigerated at 2°C to 8°C for up to 3 months. For long term storage store at -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 0.02% sodium azide
• Gene Accession No.: Q80WK7, Q99P65, Q9BZD2
• Gene Symbols: SLC29A3
• Immunogen: 19 amino acid peptide near the amino terminus of human SLC29A3.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG