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SLC6A4 Rabbit anti-Human, Mouse, Rat, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA550624

Catalog No. PA550624


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Description

Description

The antibody detects endogenous levels of total SLC6A4 / 5-HTT protein.

This gene encodes an integral membrane protein that transports the neurotransmitter serotonin from synaptic spaces into presynaptic neurons. The encoded protein terminates the action of serotonin and recycles it in a sodium-dependent manner. This protein is a target of psychomotor stimulants, such as amphetamines and cocaine, and is a member of the sodium:neurotransmitter symporter family. A repeat length polymorphism in the promoter of this gene has been shown to affect the rate of serotonin uptake and may play a role in sudden infant death syndrome, aggressive behavior in Alzheimer disease patients, and depression-susceptibility in people experiencing emotional trauma.
Specifications

Specifications

SLC6A4
Polyclonal
Unconjugated
SLC6A4
Liquid
SLC6A4
Synthetic peptide corresponding to a region derived from internal residues of human solute carrier family 6 (neurotransmitter transporter), member 4
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human, Mouse, Rat
Immunohistochemistry (Paraffin)
1.6 mg/mL
PBS with 50% glycerol and 0.05% sodium azide; pH 7.3
P31645, Q60857, P31652
HTT, 5HTT, OCD1, SERT, 5-HTT, SERT1, hSERT, 5-HTTLPR
Rabbit
IgG
100 μL
-20°C
Primary
15567, 25553, 6532
Documents
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