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SLC6A8 Rabbit anti-Human, Polyclonal, Proteintech Non-distribution product as customer accommodation.

Rabbit Polyclonal Antibody

Manufacturer:  Proteintech Group IncSupplier Diversity Partner 202991AP

Catalog No. 50-173-2814


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Description

Description

SLC6A8 (solute carrier family 6 member 8), also known as CT1 (creatine transporter 1), CRT or CRTR, is a 635 amino acid multi-pass plasma membrane protein that belongs to the sodium/neurotransporter (SNF) family. Expressed in a variety of tissues including kidney, skeletal muscle, heart, brain, prostate, testis and colon, SLC6A8 functions to transport creatine into and out of cells, specifically those found in brain and muscle tissue. Creatine, an organic acid, occurs naturally and is essential for supplying the energy needed for proper muscle and nerve function. Defects in the gene encoding SLC6A8 lead to cerebral creatine deficiency and are the cause of X-linked creatine deficiency syndrome, a rare disorder characterized by facial anomalies, seizures and mental retardation. Multiple isoforms of SLC6A8 exist due to alternative splicing events.
Specifications

Specifications

SLC6A8
0.31 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
P48029
Creatine transporter 1, CRT, CRTR, CT1, SLC6A8
Rabbit
IgG
150 μL
-20°C
Primary
6535
Western Blot
Unconjugated
SLC6A8
Liquid
SLC6A8
SLC6A8 Fusion Protein Ag14110
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Human
Documents
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