SLMAP Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Supplier:  Thermo Scientific PA589784

Catalog No. PIPA589784

Description

Immunogen sequence: IDTENLREEK DSEITSTRDE LLSARDEILL LHQAAAKVAS ERDTDIASLQ EELKKVRAEL ERWRKAASEY EKEITSLQNS FQLRCQQCED QQREEATRLQ GELEKLRKEW NALETECHSL KRENVLLSSE LQRQEKELHN SQKQSLELTS DLSILQMSRK ELENQVGSLK EQHLRDSADL KTLLSKAENQ AKDVQKEYEK TQTVLSELKL KFEMTEQEKQ SITDELKQCK NNLKLLREKG NNKPWPWMPM L; Positive Samples: Mouse heart, Rat heart; Cellular Location: Cell membrane, Cytoplasm, Single-pass type IV membrane protein, centrosome, cytoskeleton, microtubule organizing center, sarcolemma

Sarcolemmal membrane associated protein (SLMAP) is a tail-anchored membrane protein involved in the docking and membrane fusion process via protein-protein interactions. Deregulation of SLMAP expression plays an important role in type 2 diabetes, and changes in SLMAP expression are linked to hyperglycemia and diabetes. SLMAPs are components of cardiac membranes and have been identified as a novel regulator of cardiac function. There are several isoforms of SLMAPs with varying molecular size (35, 45, 63, and 83-91 kDa) as a result of alternative splicing. The short 35- kDa isoform is predomitly expressed in cardiac and slow-twitch skeletal muscle, while the 83- to 91- kDa isoform is ubiquitous.

Specifications

• Antigen: SLMAP
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Slmap
• Gene Symbols: Slmap
• Immunogen: Recombit fusion protein containing a sequence corresponding to amino acids 540-790 of human SLMAP
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

• Applications: Western Blot
• Concentration: 3.58 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: P0C219, Q3URD3
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 290533, 83997
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Liquid