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SLMAP Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Supplier:  Thermo Scientific PA589784

Catalog No. PIPA589784


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Description

Description

Immunogen sequence: IDTENLREEK DSEITSTRDE LLSARDEILL LHQAAAKVAS ERDTDIASLQ EELKKVRAEL ERWRKAASEY EKEITSLQNS FQLRCQQCED QQREEATRLQ GELEKLRKEW NALETECHSL KRENVLLSSE LQRQEKELHN SQKQSLELTS DLSILQMSRK ELENQVGSLK EQHLRDSADL KTLLSKAENQ AKDVQKEYEK TQTVLSELKL KFEMTEQEKQ SITDELKQCK NNLKLLREKG NNKPWPWMPM L; Positive Samples: Mouse heart, Rat heart; Cellular Location: Cell membrane, Cytoplasm, Single-pass type IV membrane protein, centrosome, cytoskeleton, microtubule organizing center, sarcolemma

Sarcolemmal membrane associated protein (SLMAP) is a tail-anchored membrane protein involved in the docking and membrane fusion process via protein-protein interactions. Deregulation of SLMAP expression plays an important role in type 2 diabetes, and changes in SLMAP expression are linked to hyperglycemia and diabetes. SLMAPs are components of cardiac membranes and have been identified as a novel regulator of cardiac function. There are several isoforms of SLMAPs with varying molecular size (35, 45, 63, and 83-91 kDa) as a result of alternative splicing. The short 35- kDa isoform is predominantly expressed in cardiac and slow-twitch skeletal muscle, while the 83- to 91- kDa isoform is ubiquitous.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

SLMAP
Polyclonal
Unconjugated
Slmap
D330001L02Rik, KIAA1601, mKIAA1601, sarcolemma associated protein, sarcolemmal membrane-associated protein, Sarcolemmal-associated protein, Slap, Slmap, UNQ1847/PRO3577
Rabbit
Affinity Chromatography
RUO
290533, 83997
-20° C, Avoid Freeze/Thaw Cycles
Liquid
Western Blot
1.92 mg/mL
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3
P0C219, Q3URD3
Slmap
Recombinant fusion protein containing a sequence corresponding to amino acids 540-790 of human SLMAP (NP_0090902)
100 μL
Primary
Mouse, Rat
Antibody
IgG
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