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Thermo Scientific™ Lab Vision™ sm (Smith Antigen) Ab-1, Mouse Monoclonal Antibody

Provide accurate, reproducible results with the Thermo Scientific™ sm (Smith Antigen) Ab-1, Mouse Monoclonal Antibody.

$292.50 - $966.00

Specifications

Antigen sm (Smith Antigen) Ab-1
Clone Y12
Applications Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Monoclonal
Host Species Murine
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Products 10
Catalog Number Mfr. No. Formulation Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Formulation Quantity Price Quantity & Availability  
MS450B
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Thermo Scientific™
MS450B
Biotinylated Ab with BSA and Azide 1mL Each for $937.00
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MS450B0
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Thermo Scientific™
MS450B0
Biotinylated Ab with BSA and Azide 100μL Each for $292.50
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MS450B1
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Thermo Scientific™
MS450B1
Biotinylated Ab with BSA and Azide 500μL Each for $775.00
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MS450P
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Thermo Scientific™
MS450P
Purified Ab with BSA and Azide 1mL Each for $899.00
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MS450P1
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Thermo Scientific™
MS450P1
Purified Ab with BSA and Azide 500μL Each for $640.00
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MS450P1ABX
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Thermo Scientific™
MS450P1ABX
Ab without BSA/Azide (Frozen) 100μL Each for $707.00
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MS450PABX
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Thermo Scientific™
MS450PABX
Ab Without BSA/Azide (Frozen) 200μL Each for $966.00
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MS450R7
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Thermo Scientific™
MS450R7
Ready-to-use for IHC (UVLP) 7mL Each for $453.00
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MS450R1
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Thermo Scientific™
MS450R1
Ready-to-use for IHC (UVLP) 1mL This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000.
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MS450P0
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Thermo Scientific™
MS450P0
Purified Ab with BSA and Azide 100μL This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000.
N/A
Description

Description

Provide accurate, reproducible results with the Thermo Scientific™ sm (Smith Antigen) Ab-1, Mouse Monoclonal Antibody.

The sm (Smith) is an autoantigen on a series of particles composed of RNA and protein. Unlike RNP, the sm antigen is resistant to RNase, but partially sensitive to trypsin. It is involved in the pathogenesis of Systemic lupus erythematosus (SLE). Antibodies to sm are found in 20-30% of patients with SLE.

Host Species: Mouse

Clone: Y12

Isotype: IgG3/κ

Species Reactivity: Human, Pig, Rabbit, Rat and Drosophila. Others not known.

Epitope: Not determined

Molecular Weight: ~25kDa (predominant)

Positive Control: Ls174T cells, Tonsil

Cellular Localization: Nuclear Ab-1 recognizes cross-reactive epitopes on the B'/B and D polypeptides of Sm. Ab-1 precipitates the small nuclear RNAs U1, U2, U4, U5, and U6 providing direct evidence that the Sm antigen resides on all these RNA-protein complexes.

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)
  • Western Blotting
  • Immunofluorescence
  • Affinity Purification
  • Electron Microscopy

Note:

USA: RUO; Int'l: RUO

Specifications

Specifications

sm (Smith Antigen) Ab-1
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Murine
DNA Repair
IgG3 kappa
Y12
Monoclonal
RUO
Primary
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