SMAD3 Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Supplier:  Thermo Scientific PA141507

Catalog No. 01-675-332

Description

This antibody is expected to react with zebrafish, xenopus and chicken based on 90% sequence homology. Suggested positive control: human liver protein, liver lysate.

SMAD3 belongs to the SMAD family of proteins. They are similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein functions as a transcriptional modulator activated by transforming growth factor-beta and is thought to play a role in the regulation of carcinogenesis.

Specifications

• Antigen: SMAD3
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Smad3
• Gene Alias: AU022421; DKFZp586N0721; DKFZp686J10186; hMAD-3; hSMAD3; HSPC193; HsT17436; JV15-2; LDS1C; LDS3; MAD (mothers against decapentaplegic, Drosophila) homolog 3; MAD homolog 3; MAD homolog 3a; mad homolog JV15-2; mad protein homolog; MAD, mothers against decapentaplegic homolog 3; mad3; MAD-3; madh3; madh3a; madh3-A; MGC60396; mMad3; mothers against decapentaplegic homolog 3; mothers against decapentaplegic homolog 3a; mothers against DPP homolog 3; SMA- and MAD-related protein 3; SMAD; Smad 3; SMAD family member 3; SMAD family member 3 L homeolog; SMAD family member 3a; SMAD, mothers against DPP homolog 3; Smad3; smad3.L; smad3a; TGF beta response effector Smad3; TGF-beta response effector Smad3; transcription factor; transcription factor Smad3; wu:fa99e03; XELAEV_18018454mg; XenMLP; Xmad3; XSmad3
• Host Species: Rabbit
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 17127, 25631, 397260, 4088, 515125, 610902
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 0.05% sodium azide
• Gene Accession No.: P84022, P84024, P84025, Q8BUN5
• Gene Symbols: Smad3
• Immunogen: A portion of residues 100-150 of human SMAD3.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Bovine, Canine, Human, Mouse, Non-human Primate, Pig, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov