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Thermo Scientific™ Lab Vision™ SMAD4/DPC4 Ab-1, Mouse Monoclonal Antibody

Provide accurate, reproducible results with the Thermo Scientific™ SMAD4/DPC4 Ab-1, Mouse Monoclonal Antibody.

Specifications

Antigen SMAD4/DPC4 Ab-1
Clone SMD46; same as DCS-46
Applications Immunofluorescence, Immunoprecipitation, Western Blot
Classification Monoclonal
Format Concentrated
View More Specs

Products 1
Catalog Number Mfr. No. Concentration Conjugate Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Concentration Conjugate Quantity Price Quantity & Availability  
MS865P0
View Documents
Thermo Scientific™
MS865P0
200μg/mL Unconjugated 100μL This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000.
N/A
Description

Description

Provide accurate, reproducible results with the Thermo Scientific™ SMAD4/DPC4 Ab-1, Mouse Monoclonal Antibody.

DPC4 (also named SMAD4; small mothers against decapentaplegic deleted in pancreatic carcinoma). The family of SMAD molecules comprises essential mediators of transforming growth factor β (TGF-β) signaling. To date, seven members of this family have been identified, each of which plays a specific and separate role in mediating TGF-β superfamily gene transcription. At least two different members, Smad2 and Smad4/DPC4, have been implicated in human cancer and appear to have tumor-suppressor functions whose inactivation may play an important role in the histogenesis of pancreatic and colorectal malignancy and possibly other human cancers as well.

Host Species: Mouse

Clone: SMD46; same as DCS-46

Isotype: IgG1

Species Reactivity: Human. Others not known.

Epitope: Not determined

Immunogen: Purified recombinant DPC4 protein

Molecular Weight: 60kDa

Positive Control: Ls174T, HT29, Raji, Jurkat cells

Cellular Localization: Nuclear

Recommended for:

Western Blotting

Immunofluorescence

Immunoprecipitation (Native and denatured)

Note:

USA: RUO; Int'l: RUO

Specifications

Specifications

SMAD4/DPC4 Ab-1
Immunofluorescence, Immunoprecipitation, Western Blot
Concentrated
RUO
Primary
IgG1
SMD46; same as DCS-46
Monoclonal
Murine
Cancer and Tumor Biology
Purified recombinant DPC4 protein
SDS
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