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SMANT hydrochloride, Tocris Bioscience™

Catalog Number 466250
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Quantity:
10 mg
50 mg
This item is not returnable. View return policy
1177600-74-6
C16H24BrClN2O
375.735
XQESCHFXROUCOQ-OEEJBDNKSA-N
smant hydrochloride
91885426
N-(4-bromophenyl)-3-[(3S,5R)-3,5-dimethylpiperidin-1-yl]propanamide;hydrochloride
CC1CC(CN(C1)CCC(=O)NC2=CC=C(C=C2)Br)C.Cl
This item is not returnable. View return policy
1177600-74-6
C16H24BrClN2O
375.735
XQESCHFXROUCOQ-OEEJBDNKSA-N
smant hydrochloride
91885426
N-(4-bromophenyl)-3-[(3S,5R)-3,5-dimethylpiperidin-1-yl]propanamide;hydrochloride
CC1CC(CN(C1)CCC(=O)NC2=CC=C(C=C2)Br)C.Cl

Inhibits Smoothened (Smo) accumulation

Inhibitor of Smoothened (Smo) signaling via a unique mechanism. Inhibits Shh-induced accumulation of Smo::EGFP fusion protein in the primary cilium (IC50 = 1.1 μM). Inhibits both wild-type Smo and an oncogenic form (SmoM2) with similar efficacy.
Formula Weight 375.73
Percent Purity >99%
Quantity 50 mg
Chemical Name or Material SMANT hydrochloride
Recommended Storage Desiccate at Room Temperature
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