SMARCA2 / BRM Rat anti-Human, Mouse, Clone: 1H7A10, Active Motif™
Rat Monoclonal Antibody
Manufacturer: Active Motif 39806
DescriptionSMARCA2 encodes a protein that is a member of the SWI/SNF family of proteins and is highly similar to the brahma protein of Drosophila. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI, which is required for transcriptional activation of genes normally repressed by chromatin. Two transcript variants encoding different isoforms have been found for this gene, which contains a trinucleotide repeat (CAG) length polymorphism.
|SMARCA2 / BRM|
|ChIP assay, Immunocytochemistry, Immunofluorescence|
|70mM tris with 0.07mM EDTA, 105mM NaCl, 30% glycerol, 31mM glycine and 0.035% sodium azide; pH 8|
|2610209L14Rik; ATP-dependent helicase SMARCA2; BAF190; Baf190b; brahma; BRG1-associated factor 190B; Brm; FLJ36757; global transcription activator homologous sequence; hBRM; hSNF2a; MGC74511; NCBRS; Probable global transcription activator SNF2L2; Protein brahma homolog; SMARCA2; SNF2; SNF2/SWI2-like protein 2; SNF2A; SNF2alpha; SNF2-alpha; SNF2L2; SNF2LA; Sth1p; subunit of the SWI/SNF chromatin remodeling complex; sucrose nonfermenting 2-like protein 2; SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin a2; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2; SWI2|
|This SMARCA2 / BRM antibody was raised against a recombinant protein corresponding to amino acids 48-214 of mouse BRM.|
|-20°C, Avoid Freeze/Thaw Cycles|
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