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SMC1A Mouse anti-Human, Mouse, Clone: OTI11E1, lyophilized, TrueMAB™ Non-distribution product as customer accommodation.

Mouse Monoclonal Antibody

Manufacturer:  OriGeneSupplier Diversity Partner CF809790

Catalog No. 50-166-9718


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Description

Description

Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

Structural Maintece of Chromosomes (SMC) family proteins play critical roles in various nuclear events that require structural changes of chromosomes, including mitotic chromosome organization, DNA recombination and repair and global transcriptional repression. The chromo proteins are conserved in eukaryotes and lead to mitotic chromosome segregatior defects. This suggests a critical function of SMC family proteins in mitotic chromosome dynamics. SMC1 and SMC3 form a heterodimeric complex required for metaphase progression in mitotic cells. Specifically this SMC1/SMC3 complex is responsible for sister chromatid cohesion during metaphase. Mutations in the gene can lead to Cornelia de Lange syndrome 2.
Specifications

Specifications

SMC1A
Monoclonal
Unconjugated
SMC1A
Lyophilized
Smc1a
Human recombit protein fragment corresponding to amino acids 889-1016 of human SMC1A produced in E.coli.
Affinity Chromatography
RUO
Antibody
Monoclonal
Human, Mouse
Immunohistochemistry (Paraffin), Western Blot
OTI11E1
PBS with 8% trehalose and no preservative; pH 7.3
Q14683, Q9CU62
CDLS2, DXS423E, SB1.8, SMC1, SMC1L1, SMC1alpha, SMCB
Mouse
IgG2b
100 μg
-20° C, Avoid Freeze/Thaw Cycles
Primary
24061, 8243
SDS
Documents
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