SMC2 Monoclonal Antibody (E1M), Invitrogen™

Mouse Monoclonal Antibody

Supplier:  Thermo Scientific MA112643

Catalog No. 01-674-025

Description

A suggested positive control for this product is HeLa cells.

CAP-E and CAP-C (Chromosome Associated Protein-E & C) are also SMC (Structural Maintenance of Chromosome) family members that form a heterodimeric complex required for mitotic chromosome condensation to achieve proper segregation of genetic information during subsequent cell division. hCAP-C/hCAP-E is a component of a multiprotein complex called condensin that interacts with phosphorylation of Histone H3 resulting in the mitotic chromosome condensation. The distribution patterns of the two heterodimeric complexes in interphase nucleus indicate independent behavior of the two complexes during cell cycle. These results suggest that the two distinct complexes are involved in different aspects of mitotic chromosome organization in humar cells.

Specifications

• Antigen: SMC2
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 0.08% sodium azide
• Gene Accession No.: O95347
• Gene Symbols: SMC2
• Immunogen: Recombinant protein corresponding to aa 523-768 of human CAP-E.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

• Applications: Western Blot
• Clone: E1M
• Conjugate: Unconjugated
• Gene: SMC2
• Gene Alias: 5730502P04Rik; AI255214; AW545314; CAP E; CAPE; CAP-E; Chromosome-associated protein E; FGF-inducible protein 16; fibroblast growth factor inducible 16; Fin16; FLJ10093; hCAP-E; PRO0324; SMC protein 2; Smc2; SMC-2; SMC2 (structural maintenance of chromosomes 2, yeast)-like 1; SMC2 protein; SMC2 structural maintenance of chromosomes 2-like 1; Smc2l1; structural maintenance of chromosomes (SMC) family member, chromosome-associated protein E; structural maintenance of chromosomes 2; structural maintenance of chromosomes protein 2; XCAP-E homolog
• Host Species: Mouse
• Purification Method: Protein A/G
• Regulatory Status: RUO
• Gene ID (Entrez): 10592
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Liquid

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov