SMC2 Rabbit anti-Human, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA550767
The antibody detects endogenous levels of total SMC2 protein.CAP-E and CAP-C (Chromosome Associated Protein-E & C) are also SMC (Structural Maintece of Chromosome) family members that form a heterodimeric complex required for mitotic chromosome condensation to achieve proper segregation of genetic information during subsequent cell division. hCAP-C/hCAP-E is a component of a multiprotein complex called condensin that interacts with phosphorylation of Histone H3 resulting in the mitotic chromosome condensation. The distribution patterns of the two heterodimeric complexes in interphase nucleus indicate independent behavior of the two complexes during cell cycle. These results suggest that the two distinct complexes are involved in different aspects of mitotic chromosome organization in humar cells.
|Synthetic peptide corresponding to a region derived from internal residues of human structural maintece of chromosomes 2|
|Antigen affinity chromatography|
|PBS with 50% glycerol and 0.05% sodium azide; pH 7.3|
|CAP-E, CAPE, FLJ10093, SMC2L1, hCAP-E|
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