SMCHD1 Mouse anti-Human, Clone: CL4265, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA524708
Immunogen sequence: DNGRGMTSKQL NNWAVYRLSK FTRQGDFESD HSGYVRPVPV PRSLNSDISY FGVGGKQAVF FVGQSARMIS KPADSQDVHE LVLSKED Highest antigen sequence identity to the following orthologs - mouse 97%, rat 98%.Required for maintece of X inactivation in females and hypermethylation of CpG islands associated with inactive X. Involved in a pathway that mediates the methylation of a subset of CpG islands slowly and requires the de novo methyltransferase DNMT3B. Required for DUX4 silencing in somatic cells.
|PBS with 40% glycerol and 0.02% sodium azide; pH 7.2|
|Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Immunocytochemistry, Immunofluorescence, Immunohistochemistry|
|Recombit Human SMCHD1|
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