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SMO Rabbit anti-Human, Polyclonal, Proteintech Non-distribution product as customer accommodation.

Rabbit Polyclonal Antibody

Manufacturer:  Proteintech Group IncSupplier Diversity Partner 207871AP

Catalog No. 50-173-3085


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Description

Description

Smoothened drosophila homolog (SMOH) is a serpentine protein belonging to the G-protein coupled receptor Fz/Smo family with 787 aa, seven transmembrane G protein-coupled receptors with 4 glycosylation sites and a putative extracellular amino terminus. Smoothened activated by b-Arrestin 2 and GRK2 acts as a receptor for Shh, the Sonic hedgehog gene product, and is a positive regulator of hedgehog signaling pathway along with the smoothened inhibitor patched protein (PTCH) and regulates vertebrate developmental processes, cellular proliferation and differentiation by activating transcription factor Gli. Smoothened mutants are known to cause sporadic basal cell carcinoma of the skin. It is known to express widely in heart and brain.
Specifications

Specifications

SMO
0.44 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Q99835
Gx, Protein Gx, SMO, SMOH, Smoothened homolog
Rabbit
IgG
150 μL
-20°C
Primary
6608
Immunohistochemistry (Paraffin)
Unconjugated
SMO
Liquid
SMO
SMO Fusion Protein Ag14322
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Human
Documents
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