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SMTN Rabbit anti-Human, Mouse, Polyclonal, Proteintech Non-distribution product as customer accommodation.

Rabbit Polyclonal Antibody

Manufacturer:  Proteintech Group IncSupplier Diversity Partner 235671AP

Catalog No. 50-173-4096


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Description

Description

Smoothelin is a constituent of the smooth muscle cell (SMC) cytoskeleton. Antibodies directed to smoothelin are a useful tool to monitor SMC differentiation. Smoothelin is exclusively expressed in fully differentiated (contractile) SMCs. RNA and protein analyses reveal a broad species distribution of this protein. Cells with SMC-like characteristics, such as myofibroblasts, myoepithelial cells, and skeletal and cardiac muscle do not contain smoothelin. Confocal scanning laser microscopy of tissue sections, as well as transfection studies, show a filamentous organization of smoothelin that is different from that of desmin and vimentin. Smoothelin colocalizes with actin stress fibers. Two tissue specific isoforms have been identified: a 59 kDa isoform specific for visceral SMC; and a 100 kDa specific for vascular SMC. Human smoothelin is encoded by a single copy gene which is located on chromosome 22.
Specifications

Specifications

SMTN
0.33 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
P53814, Q921U8
smoothelin, SMSMO, SMTN
Rabbit
IgG
150 μL
-20°C
Primary
29856, 6525
Immunohistochemistry (Paraffin), Western Blot
Unconjugated
SMTN
Liquid
SMTN
SMTN Fusion Protein Ag19983
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Human, Mouse
Documents
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