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SNAI1 Mouse anti-Human, Clone: OTI1H7, liquid, TrueMAB
Mouse Monoclonal Antibody
Manufacturer: OriGene TA506430
DescriptionZinc finger protein SNAI1 (SNAIL)is a zinc finger transcriptional repressor which down regulates the expression of the ectodermal gene within the mesoderm and functions to form the mesoderm and neural crest. It is reported that SNAI1 acts as an important factor of tumor invasion as evidenced by its role in E-cadherin down-regulation and induction of epithelial-mesenchymal transition (EMT). In human breast cancer, the expression of SNAI1 and/or the homologous SNAI2 (Slug) has been associated with E-cadherin repression, local or distant metastasis, tumor recurrence, or poor prognosis in different tumor series. It is also reported that Snail 1 protein in the stromamay be anew putative prognosis marker for colon tumors.
|PBS with 1% BSA, 50% glycerol and 0.02% sodium azide|
|SLUGH2, SNA, SNAH, SNAIL, SNAIL1, dJ710H13.1|
|-20° C, Avoid Freeze/Thaw Cycles|
|Full length human recombit protein of human SNAI1 produced in HEK293T cell.|
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