SNAI1 / Snail Monoclonal Antibody (9H2), Active Motif™

Rat Monoclonal Antibody

Supplier:  Active Motif 61367

Catalog No. 50-199-3350

Description

Zinc finger protein SNAI1 (SNAIL)is a zinc finger transcriptional repressor which down regulates the expression of the ectodermal gene within the mesoderm and functions to form the mesoderm and neural crest. It is reported that SNAI1 acts as an important factor of tumor invasion as evidenced by its role in E-cadherin down-regulation and induction of epithelial-mesenchymal transition (EMT). In human breast cancer, the expression of SNAI1 and/or the homologous SNAI2 (Slug) has been associated with E-cadherin repression, local or distant metastasis, tumor recurrence, or poor prognosis in different tumor series. It is also reported that Snail 1 protein in the stromamay be anew putative prognosis marker for colon tumors.

Specifications

• Antigen: SNAI1 / Snail
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 30% glycerol and 0.035% sodium azide; pH 7.5
• Gene Accession No.: O95863
• Gene Symbols: Snai1
• Immunogen: This antibody was raised against a full-length recombinant protein corresponding to human SNAI1.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2a

• Applications: Immunohistochemistry, Western Blot
• Clone: 9H2
• Conjugate: Unconjugated
• Gene: Snai1
• Gene Alias: AI194338; dJ710H13.1; Protein sna; Protein snail homolog 1; SLUGH2; Sna; Sna protein; Sna1; SNAH; Snai1; SNAIL; snail 1; snail 1 homolog; snail 1 zinc finger protein; snail 1, zinc finger protein; snail family transcriptional repressor 1; snail family zinc finger 1; snail homolog 1; Snail1; Zinc finger protein SNAI1
• Host Species: Rat
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 6615
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid