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Snail Mouse anti-Human, Active Motif™

Mouse Recombinant Monoclonal Antibody

Manufacturer:  Active MotifSupplier Diversity Partner 91256

Encompass

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Catalog No. 50-199-3778


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Description

Description

Zinc finger protein SNAI1 (SNAIL)is a zinc finger transcriptional repressor which down regulates the expression of the ectodermal gene within the mesoderm and functions to form the mesoderm and neural crest. It is reported that SNAI1 acts as an important factor of tumor invasion as evidenced by its role in E-cadherin down-regulation and induction of epithelial-mesenchymal transition (EMT). In human breast cancer, the expression of SNAI1 and/or the homologous SNAI2 (Slug) has been associated with E-cadherin repression, local or distant metastasis, tumor recurrence, or poor prognosis in different tumor series. It is also reported that Snail 1 protein in the stromamay be anew putative prognosis marker for colon tumors.
Specifications

Specifications

Snail
Western Blot
Unconjugated
Snai1
Liquid
Mouse
IgG2a
10 μg
-20°C, Avoid Freeze/Thaw Cycles
Primary
6615
Snai1
1 mg/mL
140mM HEPES, 32mM sodium acetate with 30% glycerol, 70mM NaCl and 0.035% sodium azide; pH 7.5
O95863
AI194338; dJ710H13.1; Protein sna; Protein snail homolog 1; SLUGH2; Sna; Sna protein; Sna1; SNAH; Snai1; SNAIL; snail 1; snail 1 homolog; snail 1 zinc finger protein; snail 1, zinc finger protein; snail family transcriptional repressor 1; snail family zinc finger 1; snail homolog 1; Snail1; Zinc finger protein SNAI1
This antibody was raised against full length recombinant human SNAI1 protein (snail homolog 1 (Drosophila).
Protein A
RUO
Antibody
Monoclonal
Human
SDS
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