SND1 Rabbit anti-Human, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA540124
Recommended positive controls: 293T and HepG2 cells. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.SND1/P100 (staphylococcal nuclease and tudor domain containing 1), also known as TudorSN, it functions in the Pim-1 regulation of Myb activity and acts as a transcriptional activatior of EBNA-2. It also interacts with EAV, NSP1,GTF2E1 and GTF2E2, and forms a ternary complex with Stat6 and POLR2A. The staphylococcal nuclease-like (SN)-domains directly interact with amino acids 1099-1758 of CBP. SND1/P100 plays an important role in the assembly of Stat6 transcriptome and stimulates IL-4-dependent transcription by mediating interaction between Stat6 and CBP.
|Recombit protein encompassing a sequence within the center region of human SND1.|
|Antigen affinity chromatography|
|Immunoprecipitation, Western Blot|
|PBS with 20% glycerol and 0.025% ProClin 300; pH 7|
|staphylococcal nuclease and tudor domain containing 1, TDRD11, p100|
|Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
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