SNRNP200 Rabbit anti-Human, Mouse, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Manufacturer: Proteintech Group Inc 238751AP
DescriptionPre-mRNA splicing is catalyzed by the spliceosome, a complex of specialized RNA and protein subunits that removes introns from a transcribed pre-mRNA segment. The spliceosome consists of small nuclear RNA proteins (snRNPs) U1, U2, U4, U5 and U6, together with approximately 80 conserved proteins. U5 snRNP contains nine specific proteins. This gene encodes one of the U5 snRNP-specific proteins. This protein belongs to the DEXH-box family of putative RNA helicases. It is a core component of U4/U6-U5 snRNPs and appears to catalyze an ATP-dependent unwinding of U4/U6 RNA duplices. Mutations in this gene cause autosomal-domit retinitis pigmentosa. Alternatively spliced transcript variants encoding different isoforms have been found, but the full-length nature of these variants has not been determined.
|PBS with 50% glycerol and 0.02% sodium azide; pH 7.3|
|ASCC3L1, BRR2, BRR2 homolog, HELIC2, KIAA0788, SNRNP200, U5 200KD|
|Immunoprecipitation, Western Blot|
|SNRNP200 Fusion Protein Ag20748|
|Antigen Affinity Chromatography|
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