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SNS 032, Tocris Bioscience™
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Quantity:
10 mg
50 mg
Description
Cyclin dependent kinase (cdk) inhibitor (reported IC50 values are 0.004 - 0.048, 0.0045 - 0.05, 0.062 - 0.29, 0.2-0.48, 0.4 and 0.45 μM for cdk9, cdk2, cdk7, cdk1, cdk5 and cdk4, respectively). Displays no activity against 190 additional kinases (IC50 >1 μM). Arrests the cell cycle at G2/M; inhibits transcription, proliferation and colony formation, and induces apoptosis in RPMI-8226 multiple myeloma cells. Prevents tumor cell-induced VEGF secretion and in vitro angiogenesis.
Specifications
Quantity | 10 mg |
Formula Weight | 380.53 |
Percent Purity | >99% |
Chemical Name or Material | SNS 032 |
Safety and Handling
Recommended Storage | Store at -20°C |
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