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SNW1 Polyclonal Antibody, Invitrogen™

Catalog No. PIPA124457
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Quantity:
50 μg
Catalog No. Quantity
PIPA124457 50 μg
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Catalog No. PIPA124457

Supplier: Thermo Scientific PA124457

Description

Rabbit Polyclonal Antibody

PA1-24457 detects SkiP in Human samples. PA1-24457 has been successfully used in Western Blot procedures. PA1-24457 immunogen corresponds to Polyclonal antibody from rabbits immunized with a synthetic peptide region of human SKIIP. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.

SKIIP (Nuclear Protein SkiP, nuclear receptor coactivator NCoA-62, ski-interacting protein) is a member of the SNW gene family, encodes a coactivator that enhances transcription from some Pol II promoters. This coactivator can bind to the ligand-binding domain of the vitamin D receptor and to retinoid receptors to enhance vitamin D-, retinoic acid-, estrogen-, and glucocorticoid-mediated gene expression. It can also interact with poly(A)-binding protein 2 to directly control the expression of muscle-specific genes at the transcriptional level. Finally, the protein may be involved in oncogenesis since it interacts with a region of SKI oncoproteins that is required for transforming activity.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SNW1
Applications Immunohistochemistry, Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Gene SNW1
Gene Accession No. Q13573
Gene Alias PPS, SKIP
Gene Symbols SNW1
Host Species Rabbit
Immunogen Polyclonal antibody from rabbits immunized with a synthetic peptide region of human SKIIP
Purification Method Antigen affinity chromatography
Quantity 50 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 22938
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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