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Selleck Chemical LLCSupplier Diversity Partner Sorafenib Tosylate 10mg 475207-59-1 Bay 43-9006  DFS Item

Manufacturer:  Selleck Chemical LLCSupplier Diversity Partner S104010MG

Sorafenib Tosylate (Bay 43-9006) is a multikinase inhibitor of Raf-1 and B-Raf with IC50 of 6 nM and 22 nM in cell-free assays, respectively. Sorafenib Tosylate inhibits VEGFR-2, VEGFR-3, PDGFR-β, Flt-3 and c-KIT with IC50 of 90 nM, 20 nM, 57 nM, 59 nM and 68 nM, respectively. Sorafenib Tosylate induces autophagy and apoptosis and activates ferroptosis with anti-tumor activity.

Catalog No. 50-621-9


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