SOX17 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Manufacturer: Proteintech Group Inc 249031AP
DescriptionSOX17, also known as transcription factor SOX-17, as the name suggests is a transcription factor or a probable transcriptional activator in the premeiotic germ cells. It belongs to the SRY-related HMG box family of transcription factors with a high-mobility group DNA-binding domain (HMG box), that plays a key role in embryogenesis and binds to the sequences 5 ft.-AACAAT- ft.3 or 5 ft.-AACAAAG-3 ft.. SOX17 plays an essential role in cardiac mesoderm specification as well as in definitive hematopoiesis, maintaining fetal hematopoietic stem cells, hematopoiesis in the fetal liver and yolk sac. Along with beta-catenin, it is known to cooperate in the regulation of transcription of endodermal genes. Defects in SOX17are known to cause a severe defects in fetal hematopoiesis.
|PBS with 50% glycerol and 0.1% sodium azide; pH 7.3|
|SOX17, Transcription factor SOX 17|
|20671, 312936, 64321|
|SOX17 Fusion Protein Ag19157|
|Antigen Affinity Chromatography|
|Human, Mouse, Rat|
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