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SOX17 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech Non-distribution product as customer accommodation.

Rabbit Polyclonal Antibody

Manufacturer:  Proteintech Group IncSupplier Diversity Partner 249031AP

Catalog No. 50-173-4608


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Description

Description

SOX17, also known as transcription factor SOX-17, as the name suggests is a transcription factor or a probable transcriptional activator in the premeiotic germ cells. It belongs to the SRY-related HMG box family of transcription factors with a high-mobility group DNA-binding domain (HMG box), that plays a key role in embryogenesis and binds to the sequences 5 ft.-AACAAT- ft.3 or 5 ft.-AACAAAG-3 ft.. SOX17 plays an essential role in cardiac mesoderm specification as well as in definitive hematopoiesis, maintaining fetal hematopoietic stem cells, hematopoiesis in the fetal liver and yolk sac. Along with beta-catenin, it is known to cooperate in the regulation of transcription of endodermal genes. Defects in SOX17are known to cause a severe defects in fetal hematopoiesis.
Specifications

Specifications

SOX17
0.32 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Q61473, Q9H6I2
SOX17, Transcription factor SOX 17
Rabbit
IgG
150 μL
-20°C
Primary
20671, 312936, 64321
Western Blot
Unconjugated
SOX17
Liquid
Sox17
SOX17 Fusion Protein Ag19157
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Human, Mouse, Rat
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