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SOX17 Mouse anti-Canine, Human, Clone: OTI3H5, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA524886

Catalog No. PIMA524886


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Description

Description

SOX17 (transcription factor SOX-17) belongs to the SRY-related HMB box family of transcription factors. It acts as a transcription regulator that binds target promoter DNA and bends the DNA. It binds to the sequences 5 ft.-AACAAT- ft.3 or 5 ft.-AACAAAG-3 ft.. SOX17 modulates transcriptional regulation via WNT3A and inhibits Wnt signaling. It promotes degradation of activated CTNNB1. SOX17 plays an essential role in the regulation of embryonic development and is required for normal looping of the embryonic hear tube and for normal development of the definitive gut endoderm. Mutations in the gene can result in vesicoureteral reflux.
Specifications

Specifications

SOX17
Monoclonal
0.5 mg/mL
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Q9H6I2
VUR3, SRY-related HMG-box transcription factor SOX17, transcription factor SOX-17
Mouse
IgG2a
100 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
486955, 64321
Immunocytochemistry, Immunofluorescence, Western Blot
OTI3H5
Unconjugated
SOX17
Liquid
SOX17
Human recombit protein fragment corresponding to amino acids 177-414 of SOX17 produced in E.coli
Affinity Chromatography
RUO
Antibody
Monoclonal
Canine, Human
Documents
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