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SPACA3 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech Non-distribution product as customer accommodation.

Rabbit Polyclonal Antibody

Manufacturer:  Proteintech Group IncSupplier Diversity Partner 211371AP

Catalog No. 50-173-3275

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SPACA3 (sperm acrosome associated 3), also known as sperm lysozyme-like protein 1, lysozyme-like protein 3, lysozyme-like acrosomal sperm-specific secretory protein ALLP-17, cancer/testis antigen 54 (CT54), LYC3, SPRASA or LYZL3, is a 215 amino acid protein that participates in the fusion and adhesion of sperm and egg plasma membrane during fertilization. Identified as a novel cancer/testis antigen in hematologic maligcies, SPACA3 has the ability to elicit B-cell immune responses in patients with cancer and is considered a potential target for immunotherapy. A member of the glycosyl hydrolase 22 family which is expressed in testis, placenta and epididymis, SPACA3 exists as two alternatively spliced isoforms; SPACA3 isoform 1 is a single-pass type II membrane protein of the sperm acrosome whereas SPACA3 isoform 2 is a secreted protein. Sperm surface membrane protein that may be involved in sperm-egg plasma membrane adhesion and fusion during fertilization. It could be a potential receptor for the egg oligosaccharide residue N-acetylglucosamine, which is present in the extracellular matrix over the egg plasma membrane. The processed form has no detectable bacteriolytic activity in vitro.


0.41 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Q8IXA5, Q9D9X8
1700025M08Rik, ALLP17, Cancer/testis antigen 54, CT54, LYC3, Lysozyme like protein 3, LYZL3, SLLP1, SPACA3, sperm acrosome associated 3, Sperm lysozyme like protein 1, SPRASA
150 μL
124912, 287557, 75622
Immunocytochemistry, Immunofluorescence, Western Blot
SPACA3 Fusion Protein Ag15589
Antigen Affinity Chromatography
Human, Mouse, Rat
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