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SPACA3 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech Non-distribution product as customer accommodation.

Rabbit Polyclonal Antibody

Manufacturer:  Proteintech Group IncSupplier Diversity Partner 211371AP

Catalog No. 50-173-3275


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Description

Description

SPACA3 (sperm acrosome associated 3), also known as sperm lysozyme-like protein 1, lysozyme-like protein 3, lysozyme-like acrosomal sperm-specific secretory protein ALLP-17, cancer/testis antigen 54 (CT54), LYC3, SPRASA or LYZL3, is a 215 amino acid protein that participates in the fusion and adhesion of sperm and egg plasma membrane during fertilization. Identified as a novel cancer/testis antigen in hematologic maligcies, SPACA3 has the ability to elicit B-cell immune responses in patients with cancer and is considered a potential target for immunotherapy. A member of the glycosyl hydrolase 22 family which is expressed in testis, placenta and epididymis, SPACA3 exists as two alternatively spliced isoforms; SPACA3 isoform 1 is a single-pass type II membrane protein of the sperm acrosome whereas SPACA3 isoform 2 is a secreted protein. Sperm surface membrane protein that may be involved in sperm-egg plasma membrane adhesion and fusion during fertilization. It could be a potential receptor for the egg oligosaccharide residue N-acetylglucosamine, which is present in the extracellular matrix over the egg plasma membrane. The processed form has no detectable bacteriolytic activity in vitro.
Specifications

Specifications

SPACA3
0.41 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Q8IXA5, Q9D9X8
1700025M08Rik, ALLP17, Cancer/testis antigen 54, CT54, LYC3, Lysozyme like protein 3, LYZL3, SLLP1, SPACA3, sperm acrosome associated 3, Sperm lysozyme like protein 1, SPRASA
Rabbit
IgG
150 μL
-20°C
Primary
124912, 287557, 75622
Immunocytochemistry, Immunofluorescence, Western Blot
Unconjugated
SPACA3
Liquid
Spaca3
SPACA3 Fusion Protein Ag15589
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Human, Mouse, Rat
Documents
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