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SPANXA1 Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA549362

Catalog No. PA549362


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Description

Description

Temporally regulated transcription and translation of several testis-specific genes is required to initiate the series of molecular and morphological changes in the male germ cell lineage necessary for the formation of mature spermatozoa. This gene is a member of the SPANX family of cancer/testis-associated genes, which are located in a cluster on chromosome X. The SPANX genes encode differentially expressed testis-specific proteins that localize to various subcellular compartments. This particular gene maps to chromosome X in a head-to-head orientation with SPANX family member A2, which appears to be a duplication of the A1 locus. The protein encoded by this gene targets to the nucleus where it associates with nuclear vacuoles and the redundant nuclear envelope. Based on its association with these poorly characterized regions of the sperm nucleus, this protein provides a biochemical marker to study unique structures in spermatazoa while attempting to further define its role in spermatogenesis. [provided by RefSeq, Jul 2008]
Specifications

Specifications

SPANXA1
Polyclonal
Unconjugated
SPANXA1
Liquid
SPANXA1
KLH conjugated synthetic peptide between 2-36 amino acids from the N-terminal region of human SPANXA1.
Antigen Affinity Chromatography, Protein A
RUO
Antibody
Polyclonal
Human
Western Blot
0.5 mg/mL
PBS with 0.09% sodium azide
Q9NS26
Sperm protein associated with the nucleus on the X chromosome A, Cancer/testis antigen 111, CT111, Nuclear-associated protein SPAN-Xa, SPAN-X, SPANX-A, SPANX family member A, SPANXA1, SPANXA
Rabbit
IgG
400 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
30014
Documents
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