SPATA13 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Manufacturer: Proteintech Group Inc 214001AP
DescriptionSPT13 acts as guanine nucleotide exchange factor (GEF) for RHOA, RAC1 and CDC42 GTPases. Regulates cell migration and adhesion assembly and disassembly through a RAC1, PI3K, RHOA and AKT1-dependent mechanism. Increases both RAC1 and CDC42 activity, but decreases the amount of active RHOA. Required for MMP9 up-regulation via the JNK signaling pathway in colorectal tumor cells. Involved in tumor angiogenesis and may play a role in intestinal adenoma formation and tumor progression.
|PBS with 50% glycerol and 0.02% sodium azide; pH 7.3|
|ASEF2, SPATA13, spermatogenesis associated 13|
|219140, 221178, 305938|
|Immunocytochemistry, Immunofluorescence, Western Blot|
|SPATA13 Fusion Protein Ag16101|
|Antigen Affinity Chromatography|
|Human, Mouse, Rat|
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