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Spectrin beta-3 Rabbit anti-Human, Mouse, Invitrogen™

Rabbit Recombinant Polyclonal Antibody

Manufacturer:  Invitrogen 711584

Catalog No. PI711584


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Description

Description

This antibody is predicted to react with Monkey, Cat and Rat. Recombit rabbit polyclonal antibodies are unique offerings from Thermo Fisher Scientific. They are comprised of a selection of multiple different recombit monoclonal antibodies, providing the best of both worlds – the sensitivity of polyclonal antibodies with the specificity of monoclonal antibodies - all delivered with the consistency only found in a recombit antibody. While functionally the same as a polyclonal antibody – recognizing multiple epitope sites on the target and producing higher detection sensitivity for low abundance targets – a recombit rabbit polyclonal antibody has a known mixture of light and heavy chains. The exact population can be produced in every lot, circumventing the biological variability typically associated with polyclonal antibody production.

Spectrins are principle components of a cell ft.s membrane-cytoskeleton and are composed of two alpha and two beta spectrin subunits. The protein encoded by this gene (SPTBN2), is called spectrin beta non-erythrocytic 2 or beta-III spectrin. It is related to, but distinct from, the beta-II spectrin gene which is also known as spectrin beta non-erythrocytic 1 (SPTBN1). SPTBN2 regulates the glutamate signaling pathway by stabilizing the glutamate transporter EAAT4 at the surface of the plasma membrane. Mutations in this gene cause a form of spinocerebellar ataxia, SCA5, that is characterized by neurodegeneration, progressive locomotor incoordination, dysarthria, and uncoordinated eye movements. [provided by RefSeq, Dec 2009]
Specifications

Specifications

Spectrin beta-3
Recombinant Polyclonal
0.5 mg/mL
PBS with 0.09% sodium azide; pH 7.2
O15020
Spectrin beta chain, non-erythrocytic 2; SPTBN2; KIAA0302; SCA5
Rabbit
IgG
100 μg
Store at 4°C short term. For long term storage
Primary
20743, 6712
Western Blot
11HCLC
Unconjugated
SPTBN2
Liquid
SPTBN2
Peptides corresponding to Human SPTBN2 (aa 1334-1351, 1733-1750)
Protein A
RUO
Antibody
Oligoclonal
Human, Mouse
SDS
Documents
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