Spectrin beta-4 Mouse anti-Human, Mouse, Rat, Clone: S393-2, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA527608
DescriptionSpectrin is the major constituent of the cytoskeletal network underlying the erthrocyte plasma membrane and determines cell shape, arrangement of transmembrane proteins and organization of organelles. It is expressed at very low levels in many tissues, with the strongest expression in the cerebellum, spinal cord, stomach, pituitary gland, liver, pancreas, salivary gland, kidney, bladder and heart. Spectrin beta 4 is a non-erythrocyte member, and is expressed in the brain and pancreatic islets and localisted to the nuclear matrix, cytoplasmic vesicles and PML nuclear bodies. Beta4 spectrins are also essential for membrane stability and the molecular organization of the nodes of Ranvier.
|PBS with 50% glycerol and 0.1% sodium azide; pH 7.4|
|BetaIV-spectrin sigma1, Non-erythrocytic spectrin beta chain 4, Non-erythroidspectrin beta chain 3, SPTBN4, SPTBN3, Spnb4, KIAA1642, EMBL BAB83243.1, Ensembl ENSRNOP00000028393|
|308458, 57731, 80297|
|Immunocytochemistry, Immunofluorescence, Immunohistochemistry (PFA fixed), Western Blot|
|Fusion protein amino acids 1621-1832 (C-terminal repeats 14 to 15) of human Beta4-spectrin|
|Human, Mouse, Rat|
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