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SPIN1 Rabbit anti-Human, Mouse, Rat, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA551065

Catalog No. PA551065


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Description

Description

SPIN1 Polyclonal Antibody detects endogenous levels of SPIN1 protein.

SPIN1 (spindlin 1), also known as SPIN or ovarian cancer-related protein (OCR), is a 262 amino acid nuclear protein suggested to play a role in regulation of the cell-cycle during the transition from gamete to embryo. A member of the SPIN/STSY family, SPIN1 localizes to interphase nucleus and mitotic chromosomes, and is modified by phosphorylation in a cell-cycle-dependent fashion. A meiotic spindle-binding protein, SPIN1 overexpression has been shown to cause defects in mitotic spindles, thereby resulting in chromosome instability and potential tumorigenesis.
Specifications

Specifications

SPIN1
Polyclonal
Unconjugated
SPIN1
Liquid
SPIN1
Synthesized peptide derived from the Internal region of human Spindlin-1.
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human, Mouse, Rat
ELISA, Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Western Blot
1 mg/mL
PBS with 0.5% BSA, 50% glycerol and 0.02% sodium azide; pH 7.4
Q9Y657, Q61142, Q4V8J7
OCR, SPIN
Rabbit
IgG
100 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
10927, 20729, 361217
Documents
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