SPIN1 Rabbit anti-Human, Mouse, Rat, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA551065
SPIN1 Polyclonal Antibody detects endogenous levels of SPIN1 protein.SPIN1 (spindlin 1), also known as SPIN or ovarian cancer-related protein (OCR), is a 262 amino acid nuclear protein suggested to play a role in regulation of the cell-cycle during the transition from gamete to embryo. A member of the SPIN/STSY family, SPIN1 localizes to interphase nucleus and mitotic chromosomes, and is modified by phosphorylation in a cell-cycle-dependent fashion. A meiotic spindle-binding protein, SPIN1 overexpression has been shown to cause defects in mitotic spindles, thereby resulting in chromosome instability and potential tumorigenesis.
|Synthesized peptide derived from the Internal region of human Spindlin-1.|
|Antigen affinity chromatography|
|Human, Mouse, Rat|
|ELISA, Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Western Blot|
|PBS with 0.5% BSA, 50% glycerol and 0.02% sodium azide; pH 7.4|
|Q9Y657, Q61142, Q4V8J7|
|-20° C, Avoid Freeze/Thaw Cycles|
|10927, 20729, 361217|
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