Invitrogen™ SPR Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5121157

Catalog No. PIPA5121157

Description

Positive test controls include: HepG2, HeLa, COS-7, Jurkat, MCF7, Mouse liver, Mouse kidney, Mouse pancreas, Rat kidney. The target is usually found in the following locations: Cytoplasm. Immunogen sequence: PLDTDMQQLA RETSVDPDMR KGLQELKAKG KLVDCKVSAQ KLLSLLEKDE FKSGAHVDFY DK.

SPR encodes an aldo-keto reductase that catalyzes the NADPH-dependent reduction of pteridine derivatives and is important in the biosynthesis of tetrahydrobiopterin (BH4). Mutations in this gene result in DOPA-responsive dystonia due to sepiaterin reductase deficiency. A pseudogene has been identified on chromosome 1.

Specifications

• Antigen: SPR
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: SPR
• Gene Alias: AA409688; ENSMUSG00000071345; Gm10328; SDR38C1; sepiapterin reductase; sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase); short chain dehydrogenase/reductase family 38C, member 1; SPR
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 20751, 29270, 6697
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 0.66 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: P18297, P35270, Q64105
• Gene Symbols: SPR
• Immunogen: A synthetic peptide corresponding to a sequence within amino acids 200-261 of human SPR (P35270).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG