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SQSTM1 Mouse anti-Human, Mouse, Clone: GT1478, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA527800

Catalog No. PIMA527800


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Description

Description

Positive Control: HepG2, A549, H1299, HCT116, Huh-7 (untreated), Huh-7 (3 µM Thapsigargin treatment for 12 hr), Huh-7 (3 µM Thapsigargin treatment for 24 hr), HepG2 (3 µM Thapsigargin treatment for 12 hr), HepG2 (3 µM Thapsigargin treatment for 24 hr), *2C4, *MEF, *MNT-1 Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.

SQSTM1 encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B signaling pathway. The protein functions as a scaffolding/adaptor protein in concert with TNF receptor-associated factor 6 to mediate activation of NF-kB in response to upstream signals. Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene. Mutations in this gene result in sporadic and familial Paget disease of bone.
Specifications

Specifications

SQSTM1
Monoclonal
1 mg/ml
PBS with no preservative
Q13501, Q64337
p62, A170, OSIL, sequestosome 1, p62B, p60, ZIP3, PDB3
Mouse
IgG2b
100 μl
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
18412, 8878
Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Frozen), Western Blot
GT1478
Unconjugated
SQSTM1
Liquid
SQSTM1
Recombit protein encompassing a sequence within the center region of human SQSTM1. The exact sequence is proprietary.
Protein G
RUO
Antibody
Monoclonal
Human, Mouse
Documents
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