SQSTM1 Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Supplier:  Thermo Scientific PA595255

Catalog No. PIPA595255

Description

Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 μg/mL.

This gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B signaling pathway. The protein functions as a scaffolding/adaptor protein in concert with TNF receptor-associated factor 6 to mediate activation of NF-kB in response to upstream signals. Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene. Mutations in this gene result in sporadic and familial Paget disease of bone.

Specifications

• Antigen: SQSTM1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Sqstm1
• Gene Alias: A170, EBI3-associated protein of 60 kDa, EBI3-associated protein p60, EBIAP, FTDALS3, hypothetical protein 1, ORCA, OSF-6, Osi, OSIL, oxidative stress induced, oxidative stress induced like, p60, p62, p62B, PDB3, phosphotyrosine independent ligand for the Lck SH2 domain p62, phosphotyrosine-independent ligand for the Lck SH2 domain of 62 kDa, PKC-zeta-interacting protein, protein kinase C-zeta-interacting protein, sb:cb621, Sequestosome 1, sequestosome-1, Sqstm1, STAP, STONE14, ubiquitin-binding protein p62, Unknown (protein for MGC:127197), zgc:85784, ZIP, ZIP3
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 113894, 18412, 8878
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Lyophilized

• Applications: Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot
• Concentration: 500 μg/mL
• Formulation: PBS with 4MG trehalose and 0.05MG sodium azide
• Gene Accession No.: O08623, Q13501, Q64337
• Gene Symbols: Sqstm1
• Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human SQSTM1/p62 (69-96aa DEDGDLVAFSSDEELTMAMSYVKDDIFR).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Non-human Primate, Rat
• Product Type: Antibody
• Isotype: IgG