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SR 1001, Tocris Bioscience™

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Quantity:
10mg
50mg
This item is not returnable. View return policy
1335106-03-0
C15H13F6N3O4S2
477.396
OZBSSKGBKHOLGA-UHFFFAOYSA-N
n-4-methyl-5-4-2,2,2-trifluoro-1-hydroxy-1-trifluoromethyl ethyl phenyl amino sulfonyl-2-thiazolylacetamide,sr hplc,n-5-4-1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl phenyl sulfamoyl-4-methyl-1,3-thiazol-2-yl acetamide
44241473
N-[5-[[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]sulfamoyl]-4-methyl-1,3-thiazol-2-yl]acetamide
CC1=C(SC(=N1)NC(=O)C)S(=O)(=O)NC2=CC=C(C=C2)C(C(F)(F)F)(C(F)(F)F)O
This item is not returnable. View return policy
1335106-03-0
C15H13F6N3O4S2
477.396
OZBSSKGBKHOLGA-UHFFFAOYSA-N
n-4-methyl-5-4-2,2,2-trifluoro-1-hydroxy-1-trifluoromethyl ethyl phenyl amino sulfonyl-2-thiazolylacetamide,sr hplc,n-5-4-1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl phenyl sulfamoyl-4-methyl-1,3-thiazol-2-yl acetamide
44241473
N-[5-[[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]sulfamoyl]-4-methyl-1,3-thiazol-2-yl]acetamide
CC1=C(SC(=N1)NC(=O)C)S(=O)(=O)NC2=CC=C(C=C2)C(C(F)(F)F)(C(F)(F)F)O

RORα/γ inverse agonist

Retinoic acid receptor-related orphan receptor (ROR) α and γ inverse agonist (Ki values are 172 and 111 nM respectively). Demonstrates no activity at RORβ or LXR. Suppresses Th17 cell differentiation and cytokine expression and reduces the severity of disease in an animal model of mulitple sclerosis.
Quantity 50mg
Formula Weight 477.4
Percent Purity >98%
Chemical Name or Material SR 1001

Recommended Storage : Store at +4°C