Tocris SR 48692
Selective non-peptide NTS1 antagonist
Manufacturer: Tocris 3721/10
DescriptionNeurotensin antagonist; selective for NTS1 over NTS2 (apparent affinity, Ke, is 36nM for NTS1). Competitively inhibits binding of [125I]-neurotensin to HT29 and N1E115 cell membranes (IC50 values are 15.3 and 20.4nM respectively). Orally bioavailable.
- Chemical Name: 2-[[[1-(7-Chloro-4-quinolinyl)-5-(2,6-dimethoxyphenyl)-1H-pyrazol-3-yl]carbonyl]amino]-tricyclo[22.214.171.124,7]decane-2-carboxylic acid
- Formula: C32H31ClN4O5
- CAS Number: 146362-70-1
- Solubility: Soluble to 20mM in DMSO
- Purity: >98
We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.
Your feedback has been submitted. Fisher Scientific is always working to improve our content for you. We appreciate your feedback.Ok