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  6. SR 8278, Tocris Bioscience™

SR 8278, Tocris Bioscience™

Catalog Number 446310
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Quantity:
10 mg
50 mg
This item is not returnable. View return policy
1254944-66-5
C18H19NO3S2
361.474
UIEBLUZPSFAFOC-UHFFFAOYSA-N
1,2,3,4-tetrahydro-2-5-methylthio-2-thienyl carbonyl-3-isoquinolinecarboxylic acid ethyl ester, ethyl 2-5-methylsulfanyl thiophene-2-carbonyl-3,4-dihydro-1h-isoquinoline-3-carboxylate, d0k1vv, sr, semisolid, ethyl 2-5-methylsulfanyl thiophene-2-carbonyl-1,2,3,4-tetrahydroisoquinoline-3-carboxylate, ethyl 2-5-methylsulfanyl thiophen-2-yl carbonyl-1,2,3,4-tetrahydroisoquinoline-3-carboxylate
53393127
ethyl 2-(5-methylsulfanylthiophene-2-carbonyl)-3,4-dihydro-1H-isoquinoline-3-carboxylate
CCOC(=O)C1CC2=CC=CC=C2CN1C(=O)C3=CC=C(S3)SC
This item is not returnable. View return policy
1254944-66-5
C18H19NO3S2
361.474
UIEBLUZPSFAFOC-UHFFFAOYSA-N
1,2,3,4-tetrahydro-2-5-methylthio-2-thienyl carbonyl-3-isoquinolinecarboxylic acid ethyl ester, ethyl 2-5-methylsulfanyl thiophene-2-carbonyl-3,4-dihydro-1h-isoquinoline-3-carboxylate, d0k1vv, sr, semisolid, ethyl 2-5-methylsulfanyl thiophene-2-carbonyl-1,2,3,4-tetrahydroisoquinoline-3-carboxylate, ethyl 2-5-methylsulfanyl thiophen-2-yl carbonyl-1,2,3,4-tetrahydroisoquinoline-3-carboxylate
53393127
ethyl 2-(5-methylsulfanylthiophene-2-carbonyl)-3,4-dihydro-1H-isoquinoline-3-carboxylate
CCOC(=O)C1CC2=CC=CC=C2CN1C(=O)C3=CC=C(S3)SC

Description

Rev-Erbα antagonist

Rev-Erbα antagonist; inhibits Rev-Erbα transcriptional repression (EC50 = 0.47 μM). Blocks activity of Rev-Erbα agonist GSK 4112 (Cat. No. 3663) in HEK293 cells. Increases expression of glucose-regulating genes, G6Pase and PEPCK in HepG2 cells.
Quantity 10 mg
Formula Weight 361.48
Percent Purity >99%
Chemical Name or Material SR 8278

Safety and Handling

Recommended Storage Store at +4°C
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