DescriptionPotent and selective LXR inverse agonist (IC50 values are 43 and 214 nM for LXRβ and LXRα, respectively). Selectively inhibits liver LXR over peripheral LXR. Exhibits selectivity for LXR over a panel of 20 other nuclear receptors, including FXR. Reduces hepatic steatosis in obese mice.
|Target: LXR-like Receptor Antagonists|
Safety and Handling
Recommended Storage : Store at 4°C
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