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SRI Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech Non-distribution product as customer accommodation.

Rabbit Polyclonal Antibody

Manufacturer:  Proteintech Group IncSupplier Diversity Partner 164711AP

Catalog No. 50-173-0967


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Description

Description

Sorcin is a 198 amino acid, soluble, resistance-related, calcium-binding cytosolic protein belonging to the penta-EF hand (PEF) family of calcium binding proteins and contains 4 EF-hand calcium-binding motifs. Human Sorcin is known to share 95% sequence identity with hamster Sorcin. It is known to associate with the sarcolemmal proteins Annexin VII, cardiac ryanodine receptors and L-type Ca2+ channels and thus influence the intracellular Ca (2+)-homeostasis. It is also important in the regulation of intracellular Ca2+ cycling and Ca2+ influx pathways in the heart and skeletal muscle during excitation-contraction. It is overproduced in many multi-drug resistance (MDR) cells and regulates cell apoptosis pathways, thus acting as a new MDR marker for prognosis of acute myeloid leukemia (AML) and a good target for anti-MDR drug development.
Specifications

Specifications

SRI
0.4 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
P30626, Q6P069
22 kDa protein, CP 22, SCN, sorcin, SRI, V19
Rabbit
IgG
150 μL
-20°C
Primary
109552, 6717, 683667
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Unconjugated
SRI
Liquid
SRI
SRI Fusion Protein Ag9553
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Human, Mouse, Rat
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