Invitrogen™ SSEA1 Monoclonal Antibody (MC-480)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA1022

Catalog No. PIMA1022

Description

SSEA1 Monoclonal Antibody for ICC/IF, IHC (F), IHC (P), Flow

CD15 (Lewis X, Le(x); stage specific embryonic antigen-1, SSEA-1) is a trisacharide determinant (3-fucosyl-N-acetyllactosamine) expressed on several glycolipids, glycoproteins and proteoglycans of various cell types, e.g. granulocytes, mast cells, monocytes, macrophages, cells of gastric mucosa, nervous system or various tumour cells. There are several variants of Lewis x, such as sialyl-Lewis x or sulphated Lewis x. Cells with high surface expression of Le(x) antigen exhibit strong self-aggregation, based on calcium-dependent Le(x)-Le(x) interaction. This process is involved for example in embryo compaction or in autoaggregation of teratocarcinoma cells. Sialyl-Le(x) and its isomer sialyl-Le(a) are ligands of selectins. CD15 expression has been extensively used to confirm diagnosis of Hodgkin's disease.

Specifications

• Antigen: SSEA1
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 1mg/mL BSA and 0.05% sodium azide
• Gene Accession No.: P22083, Q11127
• Gene Symbols: FUT4
• Immunogen: BALB/c mouse immunized with F9 teratocarcinoma stem cells (X-irradiated).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgM

• Applications: Flow Cytometry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunocytochemistry
• Clone: MC-480
• Conjugate: Unconjugated
• Gene: FUT4
• Gene Alias: FUTIV; Lewis X; SSEA-1
• Host Species: Mouse
• Purification Method: Affinity Chromatography - MBP
• Regulatory Status: RUO
• Gene ID (Entrez): 14345, 2526
• Content And Storage: -20°C
• Form: Liquid