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SSX2 Mouse anti-Human, Clone: CL3202, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA524652

Catalog No. PIMA524652


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Description

Description

Immunogen sequence: GKHAWTHRLR ERKQLVIYEE ISDPEEDDE Highest antigen sequence identity to the following orthologs: Mouse - 66%, Rat - 79%. Binds to an epitope located within the peptide sequence GKHAWTHRLRERKQL as determined by overlapping synthetic peptides.

SSX2 belongs to the family of highly homologous synovial sarcoma X (SSX) breakpoint proteins. These proteins may function as transcriptional repressors. They are also capable of eliciting spontaneously humoral and cellular immune responses in cancer patients, and are potentially useful targets in cancer vaccine-based immunotherapy. SSX1, SSX2 and SSX4 genes have been involved in the t(X;18) translocation characteristically found in all synovial sarcomas. This translocation results in the fusion of the synovial sarcoma translocation gene on chromosome 18 to one of the SSX genes on chromosome X. The encoded hybrid proteins are probably responsible for transforming activity. Two transcript variants encoding distinct isoforms have been identified for this gene.
Specifications

Specifications

SSX2
Monoclonal
1 mg/mL
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Q16385
Synovial sarcoma, X breakpoint 2, HD21, HOM-MEL-40, MGC119055, MGC15364, MGC3884, SSX, SSX2B, CT5.2a
Mouse
IgG1
100 μL
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
6757
Immunohistochemistry
CL3202
Unconjugated
SSX2
Liquid
SSX2
Recombit protein corresponding to Human SSX2
Protein A
RUO
Antibody
Monoclonal
Human
Documents
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