Stage-Specific Embryonic Antigen-1, Clone: MC-480,Millipore™ (Chemicon™)

Manufacturer: EMD Millipore MAB4301DEL

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Catalog No. 50-175-490


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    Antigen Stage-Specific Embryonic Antigen-1
    Concentration 1mg/mL
    Conjugate Unlabeled
    Cross Reactivity Human,Mouse,Rat
    Format Purified
    Host Species Mouse
    Immunogen F9 teratocarcinoma stem cells (X-irradiated)
    Isotype IgM
    Quantity 100μg
    Regulatory Status RUO
    Research Discipline Stem Cell Biology
    Primary or Secondary Primary
    Monoclonal or Polyclonal Monoclonal

    SSEA-1 is expressed on the surface of early mouse embryos, murine embryonal carcinoma cells (EC), murine embryonic stem cells (ES) and murine & human germ cells (EG). No immunoreactivity is evident with undifferentiated human EC and ES cells.Expression of SSEA-1 is down regulated following differentiation of murine EC and ES cells. In contrast, the differentiation of human EC and ES cells is characterized by an increase in SSEA-1 expression.

    Vassilieva, S. et al(2000). Establishment of SSEA-1 and Oct-4 expressing Rat embryonic Stem-like cell lines and effects of cytokines of the IL-6 family on clonal growth.Exp. Cell Res 258: 361-373

    Flow Cytometry, Immunocytochemistry, Immunofluorescence

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