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MilliporeSigma™ Stage-Specific Embryonic Antigen-1, Clone: MC-480,™ (Chemicon™)
Supplier: MilliporeSigma™ MAB4301/DEL
Description
SSEA-1 is expressed on the surface of early mouse embryos, murine embryonal carcinoma cells (EC), murine embryonic stem cells (ES) and murine & human germ cells (EG). No immunoreactivity is evident with undifferentiated human EC and ES cells.Expression of SSEA-1 is down regulated following differentiation of murine EC and ES cells. In contrast, the differentiation of human EC and ES cells is characterized by an increase in SSEA-1 expression.
Vassilieva, S. et al(2000). Establishment of SSEA-1 and Oct-4 expressing Rat embryonic Stem-like cell lines and effects of cytokines of the IL-6 family on clonal growth.Exp. Cell Res 258: 361-373
Flow Cytometry, Immunocytochemistry, Immunofluorescence
Specifications
| Stage-Specific Embryonic Antigen-1 | |
| 1mg/mL | |
| Mouse | |
| 100 μg | |
| Stem Cell Biology | |
| Human, Mouse, Rat | |
| IgM |
| Monoclonal | |
| Unconjugated | |
| F9 teratocarcinoma stem cells (X-irradiated) | |
| RUO | |
| Primary | |
| Purified |
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