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STAT5B Rabbit anti-Human, Unconjugated, Polyclonal, Active Motif™

Rabbit Polyclonal Antibody

Manufacturer:  Active MotifSupplier Diversity Partner 61138

Encompass

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Catalog No. 50-199-3175


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Description

Description

The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein mediates the signal transduction triggered by various cell ligands, such as IL2, IL4, CSF1, and different growth hormones. It has been shown to be involved in diverse biological processes, such as TCR signaling, apoptosis, adult mammary gland development, and sexual dimorphism of liver gene expression. This gene was found to fuse to retinoic acid receptor-alpha (RARA) gene in a small subset of acute promyelocytic leukemias (APLL). The dysregulation of the signaling pathways mediated by this protein may be the cause of the APLL.
Specifications

Specifications

STAT5B
Immunoprecipitation, Western Blot
Unconjugated
Stat5b
Liquid
Rabbit
IgG
10 μg
-20°C, Avoid Freeze/Thaw Cycles
Primary
6777
Stat5b
Lot-Specific
PBS with 30% glycerol and 0.035% sodium azide; pH 7.5
P51692
BOS_19070; LOC101122961; mammary gland factor STAT5B; Signal transducer and activator of transcription 5a; Signal transducer and activator of transcription 5B; STA5B; STAT; STAT5; STAT5B; transcription factor STAT5B
This STAT5B antibody was raised against a peptide in the C-terminal region of human STAT5B.
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human
SDS
Documents
Product Certifications
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