STAT6 Rabbit anti-Human, Unconjugated, Polyclonal, Active Motif™
Rabbit Polyclonal Antibody
Manufacturer: Active Motif 61548
DescriptionSTAT6 protein is a transcription factor activated by cytokines, particularly interleukin-4 and IL13. (Stat6-/-) were found to be deficient in IL-4-mediated functions including Th2 helper T-cell differentiation, expression of cell surface markers, T-cell proliferation, immunoglobulin class switching to IgE, and partial loss of IL-4 mediated proliferation. STAT6 mRNA has been detected in peripheral blood lymphocytes, colon, intestine, ovary, prostate, thymus, spleen, kidney, liver, lung and placenta. STAT6 is critically involved in Th2 immune response. STAT6 is crucial for IL-4-mediated biological responses, and naturally in two isoforms: STAT6a and STAT6c.
|-20°C, Avoid Freeze/Thaw Cycles|
|PBS with 30% glycerol and 0.035% sodium azide; pH 7.5|
|12S1644; BOS_5462; D12S1644; IL4 STAT; IL-4 Stat; IL-4-STAT; Signal transducer and activator of transcription 6; signal transducer and activator of transcription 6, interleukin-4 induced; Signal transducer and transcription activator 6; STAT; STAT, interleukin4-induced; Stat6; STAT-6; STAT6B; STAT6C; transcription factor IL-4 STAT|
|This antibody was raised against a peptide within the C-terminal region of human STAT6. This antibody detects two isoforms of STAT6.|
|Antigen affinity chromatography|
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