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STIM2 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech Non-distribution product as customer accommodation.

Rabbit Polyclonal Antibody

Manufacturer:  Proteintech Group IncSupplier Diversity Partner 211921AP

Catalog No. 50-173-3311


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Description

Description

In T lymphocytes, the sole pathway for Ca++ entry following antigen-receptor binding is through store-operated Ca++-release-activated Ca++ (CRAC) channels. These channels are made up of the pore-forming subunit ORAI1 and the stromal interaction molecule 1 (STIM1), a protein that functions as a Ca++ sensor and activates the CRAC channels, migrating to the plasma membrane from endoplasmic reticulum (ER)-like sites which act as the Ca++ store. A related molecule, STIM2, acts to inhibit the STIM1-mediated store-operated Ca++ entry, and can form complexes with STIM1, suggesting they may play a coordinated role in controlling Ca++ entry. At least three isoforms of STIM2 are known to exist. This STIM2 antibody is predicted to have no cross-reactivity to STIM1.
Specifications

Specifications

STIM2
0.35 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
P83093, Q9P246
KIAA1482, STIM2, stromal interaction molecule 2
Rabbit
IgG
150 μL
-20°C
Primary
116873, 117087, 57620
Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Unconjugated
STIM2
Liquid
STIM2
STIM2 Fusion Protein Ag15530
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Human, Mouse, Rat
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