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SU 9516, Tocris Bioscience™ Available on GSA/VA Contract for Federal Government customers only.

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Quantity:
10mg
50mg
This item is not returnable. View return policy
377090-84-1
C13H11N3O2
241.25
QNUKRWAIZMBVCU-WCIBSUBMSA-N
z-3-1h-imidazol-5-yl methylene-5-methoxyindolin-2-one,3z-3-1h-imidazol-5-ylmethylene-5-methoxy-1h-indol-2 3h-one,3z-3-1h-imidazol-5-ylmethylidene-5-methoxy-2,3-dihydro-1h-indol-2-one,3-1-3h-imidazol-4-yl-meth-z-ylidene-5-methoxy-1,3-dihydro-indol-2-one,su9,imidazole indolinone driv.,d0l3fk,regid_for_cid_659436,z-1,3-dihydro-3-1h-imidazol-4-ylmethylene-5-methoxy-2h-indol-2-one,regid_for_cid_5289419
5289419
(3Z)-3-(1H-imidazol-5-ylmethylidene)-5-methoxy-1H-indol-2-one
COC1=CC2=C(C=C1)NC(=O)C2=CC3=CN=CN3
This item is not returnable. View return policy
377090-84-1
C13H11N3O2
241.25
QNUKRWAIZMBVCU-WCIBSUBMSA-N
z-3-1h-imidazol-5-yl methylene-5-methoxyindolin-2-one,3z-3-1h-imidazol-5-ylmethylene-5-methoxy-1h-indol-2 3h-one,3z-3-1h-imidazol-5-ylmethylidene-5-methoxy-2,3-dihydro-1h-indol-2-one,3-1-3h-imidazol-4-yl-meth-z-ylidene-5-methoxy-1,3-dihydro-indol-2-one,su9,imidazole indolinone driv.,d0l3fk,regid_for_cid_659436,z-1,3-dihydro-3-1h-imidazol-4-ylmethylene-5-methoxy-2h-indol-2-one,regid_for_cid_5289419
5289419
(3Z)-3-(1H-imidazol-5-ylmethylidene)-5-methoxy-1H-indol-2-one
COC1=CC2=C(C=C1)NC(=O)C2=CC3=CN=CN3

Potent cdk2 inhibitor

Cyclin-dependent kinase (cdk) inhibitor (reported IC 50 values are 0.02 - 0.03, 0.04 - 0.2, 0.2 - 1.7 and 0.9 μM for cdk2, cdk1, cdk4 and cdk9, respectively). Inhibits pRb phosphorylation causing enhanced pRB/E2F complex formation and induces G1 and G2-M cell cycle arrest. Transcriptionally downregulates Mcl-1 and has antiproliferative, cytostatic and pro-apoptotic effects in vitro.

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Quantity 10mg
Formula Weight 241.25
Percent Purity >99%
Chemical Name or Material SU 9516

Recommended Storage : Store at +4°C