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SUMO1 Mouse, Clone: SM1/495, Novus Biologicals™

Mouse Monoclonal Antibody

Manufacturer:  Novus BiologicalsSupplier Diversity Partner NBP2329010.2MG

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Catalog No. NBP232901B

This item has been discontinued and is no longer available. Please call customer service for assistance: 1-800-766-7000.


Description

Description

SUMO1 Monoclonal antibody specifically detects Antigen in Human, Rat samples. It is validated for Flow Cytometry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blotting.
Specifications

Specifications

SUMO1
SM1/495
Western Blot 0.5-1ug/ml, Flow Cytometry 0.5-1ug/million cells, Immunocytochemistry/Immunofluorescence 0.5-1ug/ml, Immunohistochemistry-Paraffin 0.5-1.0ug/ml, Immunohistochemistry-Frozen 0.5-1.0ug/ml, SDS-Page
P63165
DAP1, GAP modifying protein 1, GAP-modifying protein 1, GMP1SMT3CSMT3H3OFC10UBL1PIC1, SENP2, sentrin, small ubiquitin-related modifier 1, SMT3, SMT3 homolog 3, SMT3 suppressor of mif two 3 homolog 1 (S. cerevisiae), SMT3 suppressor of mif two 3 homolog 1 (yeast), Smt3C, SUMO-1, Ubiquitin-homology domain protein PIC1, ubiquitin-like 1 (sentrin), Ubiquitin-like protein SMT3C, Ubiquitin-like protein UBL1
Mouse
IgG1 Kappa
0.2 mg
Alzheimers Research, Core ESC Like Genes, Neuroscience, Stem Cell Markers
Primary
7341
Human, Rat
Western Blot, Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen)
Unconjugated
PBS with 0.05% BSA. with 0.05% Sodium Azide
Purified
SUMO1
Recombinant human SUMO1 protein
Protein A purified
RUO
Store at 4C.
Monoclonal
This MAb is specific to SUMO-1 and shows no cross-reaction with either SUMO-2 or SUMO-3. The small ubiquitin-related modifier (SUMO) proteins, which include SUMO-1, SUMO-2 and SUMO-3, belong to the ubiquitin-like protein family. Like ubiquitin, the SUMO proteins are synthesized as precursor proteins that undergo processing before conjugation to target proteins. Also, both utilize the E1, E2, and E3 cascade enzymes for conjugation. However, SUMO and ubiquitin differ with respect to targeting. Ubiquitination predominantly targets proteins for degradation, whereas sumoylation targets proteins to a variety of cellular processing, including nuclear transport, transcriptional regulation, apoptosis and protein stability. The unconjugated SUMO-1 protein localizes to the nuclear membrane.
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